Pericardial Mesothelioma Cancer Guide

Pericardial mesothelioma is a rare cancer that develops in the pericardium around the heart. Pericardial mesothelioma is associated with asbestos exposure. Symptoms include chest pains, irregular heartbeats, and shortness of breath.

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What Is Pericardial Mesothelioma?

Pericardial mesothelioma is a rare form of mesotelioma that develops in the tissue around the heart. It is an aggressive cancer that is difficult to diagnose and treat.

Pericardial mesothelioma gets its name from the part of the body where it is found, the pericardium. The pericardium is the protective double-walled sac that surrounds the heart.

This sac contains pericardial fluid, protecting the heart and its associated veins and arteries from external jolts or shocks.

How Rare Is Pericardial Mesothelioma?

According to a study published in the Texas Heart Institute Journal, pericardial tumors account for less than one percent of all types of mesothelioma. Mesothelioma itself is rare. There have been fewer than 200 cases of pericardial mesothelioma ever reported.

What Are the Symptoms of Pericardial Mesothelioma?

In general, the cancer forms on the outer lining of the pericardium. As a tumor grows over a period, it can take as long as five decades before síntomas del mesotelioma become apparent.

The problem with diagnosing this disease is that symptoms are similar to other diseases of the heart, which are much more common. Typical early symptoms of pericardial mesothelioma include:

• Shortness of breath, especially when lying down
• Persistent coughing
• Dolores en el pecho
• Heart palpitations
• Heart murmur

As pericardial mesothelioma advances, these symptoms worsen, and new ones may appear:

• Unintentional weight loss
• Fatiga
• pérdida de masa muscular
• Fiebre
• Sudores nocturnos

Complications of Pericardial Mesothelioma

Many of the symptoms of pericardial mesothelioma arise from the common complications of tumors in the pericardium.

The most common of these is pericardial effusion, the buildup of fluid between the layers of the pericardium. This causes pain, shortness of breath, and pressure in the chest.

Pericardial mesothelioma can also lead to heart failure, which occurs when the heart’s pumping begins to weaken. This can be the ultimate cause of death for a patient with pericardial mesothelioma.

Diagnosing Pericardial Mesothelioma

Diagnosing pericardial mesothelioma begins with a physical exam and a medical history. If you have any history of asbestos exposure, tell your doctor. The next steps in making a diagnosis include:

• Echocardiogram. An echocardiogram is an ultrasound performed on the heart. This gives doctors an image of the heart and detects fluid around it.
• CT scan. Doctors can also order a CT scan to get a better image of the heart. It helps doctors identify abnormal areas of tissue that might be cancerous.
• Biopsy. If the imaging scans show abnormal tissue, the next step is to biopsy it. This means removing a small amount of fluid or tissue. A pathologist then examines the tissue sample to look for signs of cancer cells and to identify cell types as part of the diagnosis.

Common Misdiagnoses for Pericardial Mesothelioma

A study of 120 cases of pericardial mesothelioma found that three-quarters of the diagnoses were made after the patients died. This fact highlights how difficult it is to diagnose this rare cancer accurately.

Because it is so rare, doctors are likely to misdiagnose pericardia mesothelioma as a more common condition, such as:

• Heart disease
• Insuficiencia cardiaca
• Cardiac tamponade
• Cardiomyopathy
• Constrictive pericarditis
• Coronary artery disease
• Tuberculosis pericarditis

By the time a patient gets a diagnosis of pericardial mesothelioma, the cancer has likely spread beyond the pericardium and metastasized to the lymph nodes or the lungs. It is difficult to treat, and life expectancy is short.

For these reasons, it is important to seek a second opinion if you are not satisfied with your diagnosis or don’t feel a doctor is taking your concerns seriously.

What Causes Pericardial Mesothelioma?

The majority of cases of mesothelioma resulted from workplace asbestos exposure. Most of those diagnoses are mesotelioma pleural.

When workers breathed in asbestos fibers, they caused lesions in healthy tissue. The tissue became cancerous over time and created malignant tumors.

Pericardial mesothelioma can develop as a result of exposure to asbestos. Researchers have also linked pericardial mesothelioma to other contributing factors.

These risk factors include:

• Family history
• Conditions that affect the immune system
• Exposure to radiation
• Infections

How Is Pericardial Mesothelioma Treated?

Treatment for any type of mesothelioma is usually multimodal. This means doctors use a combination of therapies. Typical options include surgery, chemotherapy, radiation therapy, and immunotherapy. Surgery and chemotherapy are the most common treatment strategies for pericardial mesothelioma.

Surgery for Pericardial Mesothelioma

Surgery to remove tumors is one of the most effective ways to treat cancer. Unfortunately, many patients with pericardial mesothelioma are not eligible for surgery. The tumors are too advanced and widespread.

Those who do qualify can benefit from a cirugía called pericardiectomy. It involves the removal of part or all of the pericardium. Surgeons can also remove tumors that have spread to other tissues in the area.

Surgeons can also use a pericardiectomy as a palliative treatment. It removes fluid and pressure from the heart, which helps relieve symptoms.

Quimioterapia

Patients who undergo surgery will likely also receive chemotherapy, either to shrink tumors before the procedure or to eliminate cancer cells the surgeon could not remove.

Patients ineligible for surgery can benefit from chemotherapy to shrink tumors, relieve symptoms, and extend life expectancy. The standard chemotherapy combination is pemetrexed with cisplatin.

Studies have shown that chemotherapy is the best treatment for extending survival times for patients with pericardial mesothelioma.

What Is the Prognosis for Pericardial Mesothelioma?

According to the Mesothelioma Applied Research Foundation (MARF), around half of all mesothelioma patients can expect to live for a period that ranges from eight months to around a year and a half.

The life expectancy of a person with pericardial mesothelioma is less than six months on average. One of the most critical factors in prognosis is the cancer’s stage. Pericardial mesothelioma is almost always diagnosed in later stages when the cancer has spread, and treatment options are limited.

Each patient’s prognosis is unique and depends on age, general health, diet, and other lifestyle issues like smoking. Also vital is treatment. Patients who get treated sooner and choose the most aggressive treatments available generally have a longer survival time.

If you received a diagnosis of pericardial mesothelioma, find out what you can do to improve your outcome. Talk to your medical team about treatment options and get started as soon as possible.

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