The prognosis for pleural mesothelioma patients has always been difficult when determining the long-term outlook from from person to person. Yet, a new statistical model shows promise that mesothelioma patients may be able to get a more precise, individualized prognosis.
According to Dr. Giovanni Leuzzi, an Italian physician of the National Cancer Institute in Rome, researchers in Italy have been working on creating a more accurate way to provide the correct prognosis to individual mesothelioma patients. So far, says Dr. Leuzzi, the results are promising.
“Our model could be easily applied. We have factors that may be combined into a scoring system to better predict the outcome after surgery.”
However, even the most experienced mesothelioma have always had a hard time when giving an individual prognosis. In some instances, patients will go on to defy the odd. While they’re given a prognosis of 18 months, they’ve lived more 5 years.
So, how will a new model help with mesothelioma prognosis? According to Dr. Leuzzi, the model will help better identify those with a low prognosis and a more favorable prognosis.
“This model may be useful to identify two different groups of [mesothelioma] cancer patients: Those with favorable prognoses and those with poor prognoses.”
The Long-Term Survival Model
The Long-Term Survival Model (LTS) was used on over 400 mesothelioma patients who elected for extrapleural pneumonectomy surgery (EPP). After studying the result of the study, which was conducted between January 2000 through December 2010, researchers concluded that the long-term survivors after the surgery had many factors in common, including their age (under 61), their lack of occupational exposure to asbestos, and their epithelioid histology (more likely to have a higher history).
Dr. Leuzzi feels that LTS has the potential to help patients in numerous ways, including helping them get the best treatment possible.
“Patients can benefit in many ways. The patient will be elucidated by the calculated prognosis. And the post-surgical treatment may be modified or tailored, according to the prognostic group in which the patient falls.”
One patients are grouped into either poor prognosis or favorable prognosis, better clinical trials, and subsequently, better treatment options may become available. Additionally, the model can help physicians discern which mesothelioma patients would be the best candidates for more aggressive treatment options, such as surgery and more rigorous therapy options. Dr. Leuzzi added that
“This is very interesting. The results are different from previous analyses evaluating the long-term survival of the whole cohort. The findings are preliminary, but we found factors that may be combined into a scoring system that will work much better for patients.”
Additional Help and Resources for Mesothelioma Patients
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