Can Aspirin Slow Down Mesothelioma Development?

Researchers at the University of Australia were disappointed when they determined that aspirin could not prevent mesothelioma from developing nor could it extend survival rates of those who already live with it. The good news, however, is that it may be able to slow down the disease’s latency period, at least temporarily.

According to reports, researchers at the University of West Australia’s School of Public Health and the National Centre for Asbestos Related Diseases state that NSAIDs such as aspirin, as well as COX-2 inhibitors were not effective in stopping the development of mesothelioma when tested on mice. However, research indicates that the time of mesothelioma development was significantly altered in the mice that were given aspirin.

The theory was tested by giving mice daily feeds of either 50mg or 250mg of aspirin, while also giving the medication over 1,700 people, living in Witenoom, Australia, who have been exposed to asbestos while working. According to  Dr. Cleo Robinson, the lead researcher of the study, even though aspirin helps with inflammation, it will not help people battle the disease long-term.

“Aspirin did not alter the rate of disease development or increase the length of time that mice survived,” said Dr. Robinson. 

However, the latency period was determined to have slowed down on mice with mesothelioma. Yet, once the symptoms of mesothelioma kicked in, the development wasn’t delayed. Currently, the latency period for humans can be anywhere from 10 to 50 years, with around 30 years being the most common. Once the latency period ends and mesothelioma starts the develop, it progresses rapidly. It generally starts out by mimicking common respiratory illnesses, but eventually attacks organs, followed by difficulties in breathing, vein obstruction, blood clotting, dysphagia, and more.

“Aspirin had a small but significant effect on disease latency (the time between asbestos exposure and first evidence of disease; p<0.05) but disease progression was not affected by the continued presence of the drug,” said Dr. Cleo. 

Although the United States has a large population of people who now suffer from asbestos-related diseases, Australia currently has the highest rates of mesothelioma victims in the world, which experts state is because of the country’s extensive history of mining occupations. While United States still hasn’t totally banned the use of asbestos, Australia recently joined many other countries that have totally banned any use of asbestos at all. Unfortunately, people in the United States continue to develop asbestos-related diseases, at an alarming rate of around 2,500 per year.

If you’ve developed an asbestos-related illness due to the negligence of another party, keep in mind that you may be entitled to compensation. Many companies who supplied asbestos to job sites have now set up asbestos trust funds to compensate victims of asbestos illnesses. In fact, over $30 billion is currently available in these trust funds. For more information and for a free consultation, contact our leading mesothelioma law firm today.

For additional details on mesothelioma, including detection, causes, treatment options, and more, fill out our contact form today for a free Mesothelioma and Asbestos Guide.

Source:

http://www.lungcancerjournal.info/article/S0169-5002(14)00347-X/abstract

 

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