Aspirin May Prevent or Delay Mesothelioma

A recent report indicates that taking an aspirin per day may prevent mesothelioma from developing or help delay its growth once the disease has already started to develop.

According to a study performed by the University of Hawaii Cancer Center, aspirin has the capacity to hinder a molecule that plays a large role in the development of malignant mesothelioma. Per Haining Yang, PhD, the lead researcher in the study, mice were used in the study, but showed great promise.

“The findings were very convincing. The aspirin worked really well. It increased survival [in mice] dramatically. For anyone at high risk for mesothelioma later in life, taking aspirin might be a good option in terms of prevention.”

However, a 2012 study performed by the University of Australia’s School of Public Health indicates that aspirin can only slow down the progress, but not prevent it from developing. Per  Dr. Cleo Robinson, the lead researcher of the study, mice were also used in the study, and the aspirin had no effect on stopping mesothelioma from developing.

“Aspirin did not alter the rate of disease development or increase the length of time that mice survived. Aspirin had a small but significant effect on disease latency (the time between asbestos exposure and first evidence of disease; p<0.05) but disease progression was not affected by the continued presence of the drug.”

Regardless, Yang indicates that the newest study shows that the High-Mobility Group Box 1 (HMGB1) molecule was hindered when mice took one aspirin per day. HMGB1 is the molecule responsible to promoting the growth of malignant mesothelioma. Yet, Yang also states that aspirin works when taken early on, before the disease has progressed too much.

“For later stage disease, aspirin isn’t going to do much by itself. But in the very earliest stage of disease, and possibly in prevention, we believe it will have an effect. We have talked to families already about this. Taking aspirin might be a good idea.”

The study indicates that the average survival rate of mice with mesothelioma that didn’t take aspirin was a little over 76 days, whereas the mice that were given aspirin survived around 96 days. The study was so successful that it’s now in its clinical stages.

Warnings About Aspirin

Before you start taking aspirin, it’s important to talk to your physician. Although it’s an over-the-counter medication used to treat minor pains, taking aspirin daily may cause side effects, including:

  • Allergic reactions
  • Gastrointestinal bleeding
  • Increased risk of stroke

In addition, the United States Food and Drug Administration (FDA) warns that you should always limit alcohol consumption when taking aspirin and to limit taking supplements that can increase bleeding risks, including:

  • Fish oil
  • Gingko
  • Cat’s claw
  • Primrose oil
  • Bilberry
  • Danshen

Certain medications may also have a negative interaction with aspirin. Again, be certain to speak with your doctor prior to taking any aspirin products.

Additional Help and Resources for Asbestos Victims

If you or a loved one have been diagnosed with malignant mesothelioma or any other asbestos-related illness, keep in mind that you may be eligible for substantial compensation to help cover medical bills, pain, suffering, lost wages, and more. The first step in obtaining the compensation you deserve is to find an experienced asbestos attorney. We invite you to use our free Asbestos Attorney Locator Tool to find a leading mesothelioma lawyer in your area. 

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